Stress relief has become a primary focus when discussing the benefits of massage therapy. In recent years, massage therapy has gained recognition not only for its pain-relieving effects but also for its significant impact on biochemistry and mental health.
Research consistently highlights the positive effects of massage of stress-related hormones and neurotransmitters, indicating its potential for broader applications, including the management of migraines, mental health issues and stress relief.
This article explores the scientific evidence behind the biochemical effects of massage therapy, particularly its ability to lower cortisol levels while increasing serotonin and dopamine, resulting to stress relief. Additionally, the mental health benefits of massage for migraine sufferers are discussed, including findings that support Fullon Life’s holistic approach to wellness.
The Biochemical Impact of Massage Therapy
Massage therapy influences several key biochemical markers, such as cortisol, serotonin, and dopamine, associated with stress and mood regulation. These effects are evident across studies on various conditions, including depression, pain syndromes, autoimmune diseases, and chronic stress. According to a comprehensive review in the National Library of Medicine, massage therapy results in:

Reduced cortisol levels
Studies report an average cortisol reduction of 31% following massage sessions. Cortisol, the body’s primary stress hormone, is linked to anxiety, depression, and other stress-related conditions. Lowering cortisol levels can have profound effects on stress management and mental health. Stress relief is a key benefit of this reduction, offering a natural way to manage the body’s response to stress.
Increased serotonin and dopamine
Massage therapy is associated with an average serotonin increase of 28% and dopamine increase of 31%. These neurotransmitters are crucial in regulating mood, motivation, and pleasure. Higher serotonin and dopamine levels can improve mood stability and enhance feelings of well-being.
Stress relief is a direct result of these neurotransmitter changes, as they help counteract the negative impacts of stress on the body and mind.
These findings suggest that massage therapy has both stress-relieving (cortisol reduction) and mood-enhancing (serotonin and dopamine elevation) effects, offering a natural and holistic method for stress relief and improvement of emotional health.
Massage Therapy and Migraines – Reducing Pain and Enhancing Quality of Life
Migraines are not only physically debilitating but also deeply affect mental health. Recent studies have shown that massage therapy can help with stress relief, reduce migraine pain, improve sleep, and elevate mood by positively impacting serotonin levels and lowering stress markers.
U.S. Study on Migraine Pain and Quality of Life: In a U.S. study, 26 participants were divided into a massage group and a control group. Those who received massages twice a week for five weeks reported:
- Significantly less migraine pain
- More headache-free days
- Fewer sleep problems
- Higher serotonin levels, which are linked to improved mood and better sleep
The stress relief provided by massage therapy plays a crucial role in managing migraine symptoms and enhancing overall quality of life.

New Zealand Study on Migraine Frequency and Sleep Quality: Another 13-week study in New Zealand with nearly 50 participants also demonstrated lasting benefits. Participants in the massage group, who received weekly massages during weeks 5-10, reported:
- Less frequent migraines
- Reduced anxiety and heart rate
- Lower cortisol levels
- Enhanced coping skills and stress management
- Improved sleep quality
These findings indicate that massage therapy not only reduces the physical symptoms of migraines but also promotes mental well-being through stress relief and sleep improvement. In fact, massage therapy has been shown to be as effective as some medications used for migraine prevention, such as propranolol and topiramate, making it a viable complementary approach for migraine sufferers.
Remedial Massage and Mental Health in Migraine Sufferers
Massage therapy extends its benefits beyond physical pain relief to offer substantial mental health benefits, making it particularly valuable for migraine sufferers who often experience anxiety, stress, and depression. Migraines can create a cycle of stress and helplessness, which can worsen symptoms over time. By addressing both physical and mental health, remedial massage provides a holistic approach to managing these complex issues.
Reducing Stress and Anxiety
Remedial massage activates the body’s relaxation response, lowering cortisol and enhancing serotonin levels, which play a key role in managing stress and anxiety. Reduced stress can lead to fewer migraine triggers, as stress is a common catalyst for migraine episodes. This is especially relevant for people who experience migraines in high-stress environments, whether due to job demands, aging, or pregnancy.

Research-Backed Mental Health Benefits of Massage
A study published in Pain Medicine found that regular massage therapy reduced anxiety and stress relief among migraine sufferers, which subsequently led to a decrease in migraine frequency. This evidence reinforces the potential of remedial massage to alleviate both the physical pain and emotional distress associated with migraines, providing a comprehensive treatment that addresses mind and body.
Fullon Life’s Holistic Approach to Migraine and Mental Health
At Fullon Life, a holistic approach is taken to support clients dealing with migraines and mental health challenges. Recognising the connection between stress, migraines, and mental well-being, Fullon Life offers a calm, therapeutic environment where clients can experience stress relief and overall health. This approach aligns with research findings that highlight the importance of addressing biochemical and psychological factors to achieve lasting wellness.
Massage therapy has proven benefits that extend beyond traditional pain relief. By reducing cortisol and increasing serotonin and dopamine, it promotes stress relief, relaxation, improves mood, and supports overall mental well-being. For migraine sufferers, this approach offers a dual benefit—relief from physical pain and enhanced emotional resilience. Contact Fullon Life, located in Zillmere, to explore the combined mental and physical advantages of massage therapy for managing migraines and supporting mental health.